It's a terrifying fact: More than 47,000 people in America died of drug overdoses in 2014 — in what's been widely called an epidemic. But the biggest killer of this epidemic isn't cocaine, meth, or even heroin; it's totally legal opioid painkillers. Here's how it happened:
Recently in Psychiatry Category
Research director at Denmark’s Nordic Cochrane Centre, Professor Peter Gøtzsche, says the use of most antidepressants and dementia drugs could be halted without inflicting harm on patients. The Danish scientist’s views were published in the British Medical Journal on Tuesday.
Including Zyprexa, Zyprexa Zydis, Zyprexa Relprevv, and Symbyax
[Posted 05/10/2016]
AUDIENCE: Psychiatry, Dermatology, Patient
ISSUE: FDA is warning that the antipsychotic medicine olanzapine can cause a rare but serious skin reaction that can progress to affect other parts of the body. FDA is adding a new warning to the drug labels for all olanzapine-containing products that describes this severe condition known as Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
A search of the FDA Adverse Event Reporting System (FAERS) database identified 23 cases of DRESS reported with olanzapine worldwide since 1996, when the first olanzapine-containing product was approved. FAERS includes only reports submitted to FDA, so there are likely to be additional cases about which FDA is unaware. One patient taking olanzapine experienced DRESS and died; however, this patient was taking multiple medicines that could also have contributed to death (see the Data Summary section of the Drug Safety Communication for more information).
Comments by Brian Shilhavy
Health Impact News Editor
New York University research scholar and law professor Mary Holland recently addressed the United Nations at the 25th International Health and Environment Conference.
Professor Holland has been one of the lone voices in the U.S. addressing the legal ramifications of removing parental rights to informed consent for childhood vaccines. She has previously written for Health Impact News on this issue. See:
Killing the Messenger: U.S. Vaccine Law and PolicyProfessor Holland sees major civil rights issues involved in government vaccine policies that remove informed consent rights to refuse mandatory vaccinations. She reminds the United Nations that history has shown us the results of such overt government intrusion into personal medical rights. World-wide human rights legislation has been put into place to protect individuals from government intrusion into medical abuse, starting with the Nuremberg Code just after the atrocities of Nazi Germany after World War II.
A Sydney law firm has launched a class action on behalf of people who as children and adolescents were prescribed the anti-depressant drug Paroxetine.
Drayton Sher Lawyers has called for expressions of interest from people who were prescribed the drug, commonly known as Aropax in Australia, when they were 18 or younger.
Solicitor Tony Nikolic said hundreds of people had indicated they would join the class action, which he expects to file in the Federal Court at the end of May.
50% hike in antidepressant use in UK children
Prescriptions for antidepressants in children rose 54% between 2005 and 2012 in the UK, an international study has revealed.
The World Health Organisation (WHO) said it was ‘very concerned’ by the rise in use of the drugs in children both in the UK and other countries which it said was ‘not justified’.
Similar increases of 60% in Denmark and 49% in Germany were recorded over the same period, while antidepressant use in children went up by 26% in the USA and 17% in The Netherlands.
A rise in the use of anti-depressant drugs among children is a concern, the World Health Organization has said.
A warning in 2004 brought a fall in use of the drugs, after fears that some could lead to suicidal behaviour.
But a new study shows that between 2005 and 2012 there was a 54% increase in the number of young people prescribed them in the UK.
It also showed rises in Denmark (60%), Germany (49%), the US (26%) and the Netherlands (17%) in the same period.
'Matter of concern'
World Health Organization (WHO) director of mental health Dr Shekhar Saxena said the research, published in the European Journal of Neuropsychopharmacology, raises serious questions.
Deaths from 'Benzo' Sedatives Quietly Increasing
Prescription opioids have made headlines for skyrocketing rates of deaths from overdoses, but a new report shows that overdose deaths from another group of medications — sedatives called benzodiazepines — are also increasing.
Antidepressants can raise the risk of suicide, biggest ever review finds
Antidepressant use doubles the risk of suicide in under 18s and the risks to adults may have been seriously underestimated, researchers found
(Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports
http://www.bmj.com/content/352/bmj.i65 )Antidepressants can raise the risk of suicide, the biggest ever review has found, as pharmaceutical companies were accused of failing to report side-effects and even deaths linked to the drugs.
An analysis of 70 trials of the most common antidepressants - involving more than 18,000 people - found they doubled the risk of suicide and aggressive behaviour in under 18s.
Although a similarly stark link was not seen in adults, the authors said misreporting of trial data could have led to a ‘serious under-estimation of the harms.’
Professor Peter Gotzsche, Nordic Cochrane Centre
Maternal Antidepressant Use Tied to Autism
In a major study, published yesterday in JAMA Pediatrics, the use of SSRI antidepressants during pregnancy was found to increase the risk of autism spectrum disorder (ASD) by 87-percent. Previous studies reveal that more than 13-percent of women currently use SSRI antidepressants during pregnancy.
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